Product Details:
Prescription/Non prescription | Prescription |
Country of Origin | Made in India |
Product Details:
Minimum Order Quantity | 25 Stripe |
Dose | 4.5 mg |
Usage/Application | Personal |
Brand | LDN |
Also Gives | Third Party Manufacturing |
Packaging Size | 1*10 |
Packaging Type | STRIPS |
Form | Capsule |
Strength | This preparation has been used in the treatment of fibromyalgia (musculoskeletal pain), psoriasis (4 |
Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells. These effects may be unique to low dosages of naltrexone and appear to be entirely independent from naltrexone’s better-known activity on opioid receptors. As a daily oral therapy, LDN is inexpensive and well-tolerated. Despite initial promise of efficacy, the use of LDN for chronic disorders is still highly experimental. Published trials have low sample sizes, and few replications have been performed. We cover the typical usage of LDN in clinical trials, caveats to using the medication, and recommendations for future research and clinical work. LDN may represent one of the first glial cell modulators to be used for the management of chronic pain disorders.
Keywords: Anti-inflammatory, Chronic pain, Fibromyalgia, Glial cell modulators, Low-dose naltrexone, MicrogliaGo to:IntroductionIn this review, we will discuss the concept of using low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain conditions that are suspected to be associated with inflammatory processes. Within a specific dosage window, opioid antagonists such as naltrexone can exert a “paradoxical” analgesic effect [1]. We will further present the rationale for considering LDN as a primary example of a relatively new class of therapeutic agents called glial cell modulators. This review is intended for clinicians who are seeking additional information about the background, theory, mechanism of action, and research use of LDN. We will be focusing this discussion on LDN as a monotherapy for chronic pain. The closely related concept of ultralow-dose naltrexone involves the use of microgram, nanogram, and picogram dosages of naltrexone co-administered with opioid analgesics [2]. The approach is used to both increase the efficacy of opioid analgesia therapy and reduce some adverse side effects. Ultralow-dose naltrexone has been covered extensively in previous reviews [3] and will not be discussed here.
Go to:BackgroundNaltrexone was synthesized in 1963 as an orally active competitive opioid receptor antagonist [4]. Naltrexone is structurally and functionally similar to the opioid antagonist naloxone, but it has greater oral bioavailability and a longer biologic half-life [5]. Naltrexone HCl was approved by FDA in 1984 for the treatment of opioid addiction. The typical daily dosage for opioid addiction is 50.0–100.0 mg daily, and 50.0-mg tablets are available commercially. A more complete review of the early history of naltrexone can be found elsewhere [6].
LDN refers to daily dosages of naltrexone that are approximately 1/10th of the typical opioid addiction treatment dosage. In most published research, the daily dosage is 4.5 mg, though the dosage can vary a few milligrams below or above that common value [7–9]. At the low dosage level, naltrexone exhibits paradoxical properties, including analgesia and anti-inflammatory actions, which have not been reported at larger dosages. LDN was reported to have interesting physiological properties (primarily enhancement of endogenous opioid production) in the 1980s [6], and the treatment approach was reported to be used clinically since the mid-1980s [10]. Basic science work examining the use of opioid antagonists for treating disease states did not start to appear until the late 1980s [11], and the first published LDN trial in humans was presented in 2007 [12]. Since that time, LDN has been studied in a small number of labs and has been slowly gaining attention as a possible treatment for some chronic medical conditions.
Go to:Additional Information:
Product Details:
Minimum Order Quantity | 30 Piece |
Grade Standard | A |
Purity | 99% |
Country of Origin | Made in India |
Packaging Size | 20g |
Brand | Melacare Forte |
Packaging Type | Tube |
Strength | 20g |
Side Effects | (burning, irritation, itching and redness) |
Product Type | Finished Product |
Usage/Application | Personal |
Additional Information:
Product Details:
Minimum Order Quantity | 20 Tube |
Brand | Eflora Cream |
Packaging Size | 15 g |
Usage/Application | Personal |
Type Of Packaging | Tube |
Skin Type | Cream |
Weight | 15g |
Medicine Type | Cream |
Packaging Type | Tube |
Composition | Eflornithine (13.9% w/w) |
Additional Information:
Product Details:
Minimum Order Quantity | 25 Strip |
Brand Name | Ziverdo |
1 Kit Contains | 1 Kit Contains Strip of 17 tablets and 10 capsules |
Packaging Size | 1 x 6 kit |
Composition | Zinc acetate (50mg) + Doxycycline (100mg) + Ivermectin (12mg) |
Manufacturer | Mankind Pharma Ltd |
Manufactured By | Mankind Pharma Ltd |
Usage | Treatment of Bacterial & parasitic infections |
Form | 1 Kit Contains Strip of 17 tablets and 10 capsules |
Additional Information:
Product Details:
Minimum Order Quantity | 35 Bottle |
Brand Name | Abbott |
Manufacturer | Abbott |
Dose | 100mg |
Packaging Size | 1*25 |
Packaging Type | Bottle |
Product Type | Finished Product |
Deals in | Third Party Manufacturing |
Usage/Application | Personal |
Brand | Abbott |
Strength | Thyronorm 100mcg Tablet is a medicine used to treat an underactive thyroid gland (hypothyroidism). I |
Additional Information:
Product Details:
Minimum Order Quantity | 10 Bottle |
Brand Name | Glaxo SmithKline Pharmaceuticals Ltd |
Manufacturer | Glaxo SmithKline Pharmaceuticals Ltd |
Dose | 100mcg |
Packaging Size | 1 X 4 |
Packaging Type | Bottle |
Product Type | Finished Product |
Composition | SALT COMPOSITION Thyroxine (100mcg) SALT SYNONYMS |
Side Effects | SIDE EFFECTS OF ELTROXIN TABLET Most side effects do not require any medical attention and disappear |
Storage | Store below 30 DegreeC |
Chemical Class | Iodinated amino acid derivative |
Deals in | Third Party Manufacturing |
Type Of Medicines | Allopathic |
Usage/Application | Personal |
Brand | Glaxo SmithKline Pharmaceuticals Ltd |
Strength | Eltroxin 100mcg Tablet is a medicine used to treat an underactive thyroid gland (hypothyroidism). It |
Country of Origin | Made in India |
Additional Information:
Product Details:
Minimum Order Quantity | 12 Piece |
Packaging Size | 1x10 TAB |
Packaging Type | Box |
Dose/Strength | 150mg |
Usage/Application | Personal |
Brand | PANACUR 150MG |
Surface Finish | Finish |
Item Name | Panacur 150mg Tabs |
Country of Origin | Made in India |
Each 1.5 g bolus, 150 mg tablet, 3 g bolus contains 1.5 g, 150 mg and 3 g active Fenbendazole respectively. It is used in cattle, sheep, goat for the treatment of infestation with gastrointestinal nematodes, lungworms and tapeworms.
Composition:
The active ingredient of Panacur is Fenbendazole.
Each 1.5 gm Bolus contains 1.5 gm of active Fenbendazole
Each 3 gm Bolus contains 3 gm of active Fenbendazole
Each 150 mg tablet contains 150 mg of active Fenbendazole
Indications for use:
Infestation of cattle, buffaloes, sheep, goat & horses with gastrointestinal nematodes, lungworms and tapeworms, such as Haemonchus spp., Ostertagia spp., Trichostrongylus spp. and Cooperia spp., Nematodirus spp.
Dosage and Administration:
Cattle, buffaloes, sheep, goat: Panacur 150 mg tablet per 30 kg body weight and Panacur 1.5 gm bolus per 300 kg body weight (5 mg Fenbendazole per kg body weight).
Horses: 7.5 mg per kg body weight.
Withdrawal Period:
Meat- 8 days (Large Animals) & 14 days (Sheep, Goat), Milk- 4 days
Storage:
Store at room temperature
Presentation:
Panacur 1.5 gm bolus – A box of 15 x2
Panacur 3.0 gm bolus – A box of 10 bolus
Panacur 150 mg tablet -A box of 5 x 10
Refer to Product Leaflet for more information.
Additional Information:
Product Details:
Minimum Order Quantity | 15 Unit |
Packaging Size | v |
Brand | Nelvir |
Manufacturer | Cipla Ltd |
Composition | NEILFINAVIR MESYLATE |
Treatment | HIV |
Prescription/Non prescription | Prescription |
Form | Tablet |
Country of Origin | Made in India |
Additional Information:
Product Details:
Minimum Order Quantity | 90 Box |
Manufacturer | SHREE VENKATESH |
Dose | 40mcg |
Dose Strength | 40mg |
Brand Name | Clenbut 40 |
Packaging Size | 10x10 |
Brand | Clenbut 40 |
Deals in | Third Party Manufacturing |
Strength | 40mg |
Packaging Type | Strips |
Composition | Clenbuterol 40 Mg |
Additional Information:
Product Details:
Brand | Allergan India Pvt Ltd |
Packaging Type | Bottle |
Type Of Eyedrops | Allopathic |
Bottle Size | 3ml |
Product Details:
Minimum Order Quantity | 11 Piece |
Country of Origin | Made in India |
Additional Information:
Product Details:
Minimum Order Quantity | 25 Strip |
Medicine Type | Medicine |
Treatment | Pain killer |
Form | Tablet |
Brand | Gabapentin |
Usage/Application | Gabapentin 800 Mg Capsules is a combination medicine used for the treatment of neuropathic pain. |
Prescription/Non prescription | Non prescription |
Packaging Size | 15x10 |
Also gives | Third Party Manufacturing |
Manufacturer | Sure Health Care |
Composition | Gabapentin 800Mg |
Strength | Gabapentin 800Mg |
Gabapentin is used with other medications to prevent and control seizures. It is also used to relieve nerve pain following shingles (a painful rash due to herpes zoster infection) in adults. Gabapentin is known as an anticonvulsant or antiepileptic drug.
How to use gabapentin oralRead the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking gabapentin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor. Dosage is based on your medical condition and response to treatment. For children, the dosage is also based on weight.
If you are taking the tablets and your doctor directs you to split the tablet in half, take the other half-tablet at your next scheduled dose. Discard half tablets if not used within several days of splitting them. If you are taking the capsules, swallow them whole with plenty of water.
It is very important to follow your doctor's dosing instructions exactly. During the first few days of treatment, your doctor may gradually increase your dose so your body can adjust to the medication. To minimize side effects, take the very first dose at bedtime.
Take this medication regularly to get the most benefit from it. This drug works best when the amount of medicine in your body is kept at a constant level. Take gabapentin at evenly spaced intervals at the same time(s) each day. If you are taking this medication 3 times a day to control seizures, do not let more than 12 hours pass between doses because your seizures may increase.
Do not take this medication more often or increase your dose without consulting your doctor. Your condition will not improve any faster and the risk of serious side effects may increase.
Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.
Antacids containing aluminum or magnesium may interfere with the absorption of this medication. If you are also taking an antacid, it is best to take gabapentin at least 2 hours after taking the antacid.
Different forms of gabapentin (such as immediate-release, sustained-release, enacarbil sustained-release) are absorbed in the body differently. Do not switch from one form to the other without consulting your doctor.
Tell your doctor if your condition does not improve or if it worsens.
Additional Information:
Product Details:
Minimum Order Quantity | 10 Tube |
Country of Origin | Made in India |
Additional Information:
Product Details:
Product Type | API |
Country of Origin | Made in India |
Packaging Type | Tube |
Brand | Retino |
Usage/Application | Eye Drop |
Dosage Form | Cream |